
OHDSI Evidence Generation
• Clinical characterization:
– Descriptive statistics (e.g., natural history of a disease or
patterns of medication use)
– Quality improvement (e.g., performance measures)
• Population-level estimation
– Safety surveillance (e.g., identifying new adverse event
risks for drugs)
– Comparative effectiveness (e.g. comparing interventional
to non-interventional treatment of chronic back pain
• Patient-level prediction
– Incorporating patient medical history to provide
personalized recommendations for therapy selection,
adverse event risk, high value diagnostic studies